القيمة التشخيصية لمشعر الصدى القلبي ('Average Ee)‎ في تقييم ضغط ملء البطين الأيسر

Abstract EN

Background & Aim : Echocardiography has an important role in the assessment of left ventricular filling pressure.

It contributed in the transferring from the invasive method in the catheterization lab to the noninvasive assessment in a clinic or a hospital.

Since early studies that tried to link between echo and LV filling pressure, Av E/e' has had an important role and has been a corner stone in the guidelines that handle this issue.

However, that was without ascertaining the diagnostic accuracy, since there are three different cutoffs in three different guidelines.

For that reason, this study tried to validate the correlation between Av E/e' and LV filling pressure and its diagnostic accuracy.

Materials & Methods : In an observational cross-sectional study, 124 patients underwent transthoracic echocardiography immediately before left heart angiography.

This study used Av E/e' to estimate LV filling pressure as normal, elevated taking into account three different cutoffs : Av E/e'>13 in ESC 2016, Av E/e'>14 in EACVI/ASE 2016 and Av E/e¹215 in HFA 2019 guidelines.

Invasive LV pre-A pressure wave was used as a reference, with >12 mm Hg defined as elevated.

Results : Linear correlation between Av E/e' and LV pre-A was (P-0.0015, r=0.37), diagnostic accuracy for each cutoffs was : (Av E/e'>13 : sensitivity=0.40 and specificity=0.92 with P=0.0022 OR=3.12), (Av E/e'>14 : sensitivity=0.34 and specificity=0.92 with P-0.0045 OR-2.85) and (Av E/e¹215 : sensitivity=0.28 and specificity=0.92 with P-0.0079 OR=2.45.( Conclusion : Av E/e' had a statistically significant correlation with left ventricular filling pressure.

Among the three different cutoffs, Av E/e'>13 (in ESC 2016) was the best cutoff according to the diagnostic accuracy.