A statistical study of dermatological diseases for βThalassemia major patients using ANCOVA

Abstract EN

β-thalassemia has two types called major and minor, β-thalassemia major is more dangerous than minor and it leads to blood disorder that reduces the production of hemoglobin.

Hemoglobin is an iron-containing protein found in red blood cells and is responsible for transporting Oxygen to all of the body's cells.

The objective of this study is to evaluate and compare the effects of gender and living place of patients (Inside city, outside city) on degree of dermatological diseases for patients who have β-thalassemia major, and taking into consideration that the duration of blood transfusion (in years) was studied as a covariate for degree of dermatological diseases.

Two-way ANCOVA was used to analysis the data by applying SPSS v.25 and MS Excel.

The most important findings in this study were the gender and place of living of β-thalassemia major patients did not have significant effects on dermatological diseases (place of living has slight effects on it), at the same time duration of blood transfusion have a significant effects on dermal diseases and should be taken into consideration by dermatologists and hematologists.

Also, it is recommended to have more attention to patients living outside the cities, because there may be lack of medical centers related to thalassemia.