Lipid profile and insulin resistance in patients with type-ΙΙ diabetes mellitus

Abstract EN

Objective: To investigate the relation between dyslipidemia and insulin resistance where it is one of the metabolic disorders in patients with type-ΙΙ diabetes mellitus and compare the results with the control group.

Methodology: Blood samples were collected from (35) patients with type-ΙΙ diabetes mellitus, besides (35) healthy individuals as a control group were enrolled in this study.

The age of all subjects range from (20-50).

Serum was used in determination of glucose, insulin, lipid profile (cholesterol (Ch), triglyceride (TG), high-density lipoprotein (HDL-Ch), low-density lipoprotein (LDL-Ch) and very low-density lipoprotein (VLDL), for patients and control groups.

Insulin resistance (IR) was calculated according to homeostatic model (HOMA-IR).

Results: The results revealed a statistically significant elevation levels (P<0.001) in each of glucose, insulin, insulin resistance, Ch, TG, LDL-Ch, and VLDL, except HDL-Ch which was decreased in all patients group comparing with control group.

Recommendations: To study the Inflammatory factors and leptin and their relation to insulin resistance in type-ΙΙ DM.

Keywords: Glycoprotein; Insulin Resistance; Type-ΙΙ Diabetes Mellitus