Synthesis and characterization some of pyridine derivatives

Abstract EN

Starting compound (2,6-dimethyl-4-phenyl-3,5-diethoxy carbonyl -1,4- dihydropyridine)(1) has been prepared by treating (2mole) from ethylacetoacetate with benzaldehyde, which reacted with (2mole) hydrazine hydrate and ethanol to give hydrazide derivative(2), then converted hydrazide group to oxadiazole and triazole rings by reacted with (2mole) from carbon disulphide and potassium hydroxide to give compound(3) and with (2mole) from carbon disulphide and potassium hydroxide then (2mole) from hydrazine hydrate to give compound (4).

hydrazide derivative (2) also reacted with P-nitrobenzaldehyde and P-chlorobenzaldehyde to give (5) and (6) respectively.