تأثير السكر المتعدد الدهني Lipopolysaccharide المستخلص من بكتيريا Escherichia coli على نمو أمامي السوط لطفيلي اللشمانيا الجلدية promastigote Leishmania tropica خارج الجسم الحي in vitro

Abstract EN

In the present study, the inhibitory effect of lipopolysaccharide extracted from Escherichia coli, on growth of Leishmania tropica promastigote in vitro was investigated.The results showed that the lipopolysaccharide investigated had a marked inhibitory effect, at different concentration on growth of the promastigote .The concentration 100 μg\ml showed 41% inhibition ratio where as it is about 50% at both 25,250 μg\ml ,representing L.D.50.

The concentration 50 μg\ml showed 67% inhibition ratio .

75 & 500 μg\ml showed the highest inhibition ratio as it was 78% and 85% , respectively .

Lipopolysaccharide had the same inhibitory effect on number of cells , number of generation and the generation time.