تأثير المستخلص الكحولي لقلف نبات الصفصاف على بعض المعايير الدمية و الكيموحيوية في إناث الجرذان البيض

Abstract EN

The present study aimed to some of hematological and biochemical parameters in the female alnbino rats of exposing to different concentration of ethanolic extract of Salix acmophylla.Thus (30) animals of mature female rats were divided into six groups, the rats were proven fertile after checking their estrus cycle through daily raginal smearing for two cycles, the represented control group which intraperitonial injection with physiological solution (0.9 %/ Nacl), the first represented (G1) which injected with ethanolic extract concentration (0.85 mg/ kg) of the body weight, the second represented (G2) which injected with ethanolic extract concentration (1.7 mg/ kg) of the body weight , The third represented (G3) which injected with ethanolic extract concentration (3.4 mg/ kg), the four represented (G4) which injected with concentration (6.8 mg / kg) of the body weight, and the five concentration (13.6 mg / kg) of the body weight.After finishing the period of the experiment.

Samples of blood were collected to determine some hematological and biochemical parameters ,hematological parameters which included the haemoglobin concentration (Hb), packed cells volume (P.

C.

V.

), total and differential white blood cells (W.B.C.) w biochemical parameters included measurement of the total protein concentration, triglyceride (TG), concentration of the high density lipoprotein cholesterol (HDL-C) and concentration of low density lipoprotein cholesterol (LDL-C) ,The increasing concentration of alcoholic extract resulted to : 1- Significant decrease (p<0.05) of Hb concentration and packed cells volume (PCV).

2- Significant decrease (p<0.05) of total WBC count, neutrophils and monocytes count, besides significant increase (p<0.05) of Lymphocytes, and eosinophil count.

3- Significant decrease (p<0.05) of serum total protein, significant increase (p<0.05) of cholesterol concentration , Triglyceride, and HDL-C, LDL-C in serum of the high concentration of alcoholic extract.