Association between interleukin-5 and body mass index among Iraqi asthmatic patients

Abstract EN

Background : Asthma is an allergic hypersensitivity disease in which many mediators play a role in its pathogenecity.

One of these etiological agents is the mediators such as Interleukin-5 (IL-5).

The aim of this study to demonstrate the association between IL-5 and obesity in asthma development.

Materials & Methods: One hundred and four sera samples for asthma cases have been studied in comparison with 41 non-asthmatic bronchitis as a patient controls beside 30 apparently healthy controls.

Cytokine has been estimated using ELISA method in correlation with Body Mass Index (BMI).

Results: This study revealed a significant correlation between IL-5 concentration and BMI (P < 0.

05), particularly among females.

Conclusion: There is certain correlation between obesity and asthma accompanied by IL-5.