Evaluation the antioxidant effect of α-L- Fucose injection into rabbit periodontium
Joint Authors
al-Safi, Khulud A.
Muhammad, Chinar Anwar
Ahmad, Bakhtiar Muhyi al-Din
Source
Journal of Baghdad College of Dentistry
Issue
Vol. 25, Issue 2 (30 Jun. 2013), pp.119-124, 6 p.
Publisher
University of Baghdad College of Dentistry
Publication Date
2013-06-30
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Topics
Abstract EN
Background: α-L-Fucose is a methyl pentose sugar similar to L-galactose except for the loss of alcohol group on carbon number 6.
The objective of this study is to evaluate the biochemical and antioxidant effect of intracrevicular injection of fucose into rabbits periodontium, throughout measuring the levels of total protein (TP), total fucose (TF), protein bound fucose PBF) , Malondialdehyde (MDA) , and vitamin C in sera of fucose injected rabbit groups.( Materials and Methods: The existing study was carried out on 55 male rabbits and were divided randomly into three groups ; first group was injected with 50μl of 150mM fucose solution into gingival sulcus ; second group was injected with 50 μl of normal saline ; while the third group was not received any injection ( normal group) .Blood samples were collected from injected groups at time intervals of 1, 3 ,24 ,72, and 168 hours after injection, for measuring of serum TP, TF, , PBF , MDA, and vitamin C and compared with normal group.
Results: The results showed a significant increase in the mean concentration of TF and PBF reaching its maximum value 3hrs after injection, then it decline until reached its normal value 168 hours after injection, whereas serum total protein increased significantly only 3 hours after injection.
Also serum MDA level did not change after injection, while serum vitamin C increased immediately after fucose injection, even 72 hours after injection.
Conclusion: Intracrevicular injection of α-L- Fucose has an observable effect on TF and PBF this may give an indication about its effect on periodontal tissue and has a role in the body defence against oxidative stress, throughout increasing the production of vitamin C.
American Psychological Association (APA)
Muhammad, Chinar Anwar& al-Safi, Khulud A.& Ahmad, Bakhtiar Muhyi al-Din. 2013. Evaluation the antioxidant effect of α-L- Fucose injection into rabbit periodontium. Journal of Baghdad College of Dentistry،Vol. 25, no. 2, pp.119-124.
https://search.emarefa.net/detail/BIM-347127
Modern Language Association (MLA)
Muhammad, Chinar Anwar…[et al.]. Evaluation the antioxidant effect of α-L- Fucose injection into rabbit periodontium. Journal of Baghdad College of Dentistry Vol. 25, no. 2 (Jun. 2013), pp.119-124.
https://search.emarefa.net/detail/BIM-347127
American Medical Association (AMA)
Muhammad, Chinar Anwar& al-Safi, Khulud A.& Ahmad, Bakhtiar Muhyi al-Din. Evaluation the antioxidant effect of α-L- Fucose injection into rabbit periodontium. Journal of Baghdad College of Dentistry. 2013. Vol. 25, no. 2, pp.119-124.
https://search.emarefa.net/detail/BIM-347127
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 123-124
Record ID
BIM-347127