Thromboembolic events in ß-thalassemia major patients
Author
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 48, Issue 4 (31 Dec. 2006), pp.370-373, 4 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2006-12-31
Country of Publication
Iraq
No. of Pages
4
Main Subjects
Topics
Abstract EN
Background : Seventy eight patients with beta-thalassemia major were Collected randomly from the thalassemia center in Ibn-Al-Baldy Hospital (all of them were transfusion dependent), together with fifty six age and sex matched healthy children were collected as a control.
Aim of the study : To determine the incidence of thromboembolism among them and to evaluate the precipitating factors.
Patients and Methods : History was taken and physical examination was done.
EDTA Anticoagulated blood samples were taken prior to the next transfusion , platelet parameters were estimated for both groups using the MS-9 coulter counter .
Results : Thromboembolic events was detected in five patients (6.
41%).The main site was the central nervous system in 4 of them ( 5.
2 %) followed by the lung ,1 case ( 1.
2 %).
Associated predisposing factors were found in 3 of them (60 %).The patients had a statistically significant higher platelet counts, platelet crit, mean platelet volume and platelet distribution width than the control group.
The splenectomized had higher platelet counts ,platelet crit than the non splenectomized with nearly equal mean platelet volume and platelet distribution width, a results that is in favour of thrombosis.
Conclusions : This results suggest that beta- thalassemia patients had a hypercoagulable state which makes them susceptible to thrombosis and pulmonary embolism even in the young age group and even before splenectomy is performed.
American Psychological Association (APA)
Abbas, Sawsan S.. 2006. Thromboembolic events in ß-thalassemia major patients. Journal of the Faculty of Medicine Baghdad،Vol. 48, no. 4, pp.370-373.
https://search.emarefa.net/detail/BIM-349848
Modern Language Association (MLA)
Abbas, Sawsan S.. Thromboembolic events in ß-thalassemia major patients. Journal of the Faculty of Medicine Baghdad Vol. 48, no. 4 (2006), pp.370-373.
https://search.emarefa.net/detail/BIM-349848
American Medical Association (AMA)
Abbas, Sawsan S.. Thromboembolic events in ß-thalassemia major patients. Journal of the Faculty of Medicine Baghdad. 2006. Vol. 48, no. 4, pp.370-373.
https://search.emarefa.net/detail/BIM-349848
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 373
Record ID
BIM-349848