Paget’s disease in association with undifferentiated nasopharyngeal carcinoma
Joint Authors
Ashur, Iman
Hammami, Buthaynah
Shuqrun, Amin
Sharaf al-Din, Ilham
Shaqrun, Adil
Bin Mahfuz, Khayr al-Din
Dawud, Jamal
Guermazi, Fadil
Ghurbil, Abd al-Munim
Source
Egyptian Journal of Ear, Nose, Throat and Allied Sciences
Issue
Vol. 12, Issue 2 (31 Jul. 2011), pp.125-128, 4 p.
Publisher
Egyptian Society of Ear Nose Throat and Allied Science
Publication Date
2011-07-31
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Topics
Abstract EN
Introduction: In the case of an undifferentiated nasopharyngeal carcinoma coexisting with asymptomatic Paget’s disease it may be difficult to determine the stage.
A case of a clinically localized nasopharyngeal carcinoma coexisting with incidental Paget’s disease is reported herein.
Case report: A 51-year-old woman was admitted who presented a permanent left nasal obstruction, combined with ipsilateral epistaxis.
She was diagnosed as having a nasopharyngeal carcinoma.
The bone scan showed widespread homogenous increased remodelling throughout the skeleton.
Radiographs showed an increase in bone density and cortical thickening.
Magnetic resonance imaging (MRI) of the right leg excluded bone metastases.
We concluded that this was a localized nasopharyngeal carcinoma associated with asymptomatic Paget’s disease of the bone.
The patient showed a good response to concomitant radio chemotherapy.
Discussion: In imaging, the skeletal lesions of both nasopharyngeal cancer and Paget’s disease may closely resemble each other.
No biological markers of bone resorption or formation can differentiate between the two entities.
We used three radiological explorations to make the diagnosis.
However we believe, after reviewing the literature, that fluorodeoxyglucose positron emission tomography (FDG PET) can be helpful in this situation.
American Psychological Association (APA)
Hammami, Buthaynah& Shuqrun, Amin& Ashur, Iman& Sharaf al-Din, Ilham& Shaqrun, Adil& Bin Mahfuz, Khayr al-Din…[et al.]. 2011. Paget’s disease in association with undifferentiated nasopharyngeal carcinoma. Egyptian Journal of Ear, Nose, Throat and Allied Sciences،Vol. 12, no. 2, pp.125-128.
https://search.emarefa.net/detail/BIM-375076
Modern Language Association (MLA)
Ashur, Iman…[et al.]. Paget’s disease in association with undifferentiated nasopharyngeal carcinoma. Egyptian Journal of Ear, Nose, Throat and Allied Sciences Vol. 12, no. 2 (Jul. 2011), pp.125-128.
https://search.emarefa.net/detail/BIM-375076
American Medical Association (AMA)
Hammami, Buthaynah& Shuqrun, Amin& Ashur, Iman& Sharaf al-Din, Ilham& Shaqrun, Adil& Bin Mahfuz, Khayr al-Din…[et al.]. Paget’s disease in association with undifferentiated nasopharyngeal carcinoma. Egyptian Journal of Ear, Nose, Throat and Allied Sciences. 2011. Vol. 12, no. 2, pp.125-128.
https://search.emarefa.net/detail/BIM-375076
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 128
Record ID
BIM-375076