Hematological profile of β-thalassaemia trait in Basrah

Abstract EN

he conventional approach to qualitative and quantitative analysis of hematological molecules for the diagnosis of hemoglobinopathies requires a combination of tests ,in this study we used an automated HPLC (variant) system to study thalassaemia trait in Basrah, /I prospective study was conducted in order to determine diagnostic parameters for ^-thalassaemia trait .The mean ofhemoglobin concentration, MCV, MCH, MCHC, RBC and RDW were significantly lower while mean HbA2, RBCs count and HbF levels wen significantly higher from that of control group.

Hypochromic blood picture was found in (85 %) and interaction between (G6PD) deficiency and (5-thalassaemia was detected in (22.4 %) of the subjects.

Furthermore, there were a wide range in the levels of MCV (51-78.6) fl and HbA2 (3.9-7 %) which may be due to the coexistence of iron deficiency anaemia or to the genetic variability .