The effect of mannitol administration to kidney donor on short-term outcomes of kidney transplantation
Joint Authors
Isfarayini, Hellieh Sadat
Nurai, Navid
Asgary, Majid
Hashimian, Muhammad Rida
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 25, Issue 6 (31 Dec. 2014), pp.1154-1159, 6 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2014-12-31
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
As the cases of kidney transplant are increasing, the need to apply the factors to increase the success of transplant seems necessary.
Mannitol increases the osmotic pressure and urine volume as a protective agent on renal tubules.
We aimed to evaluate the effect of mannitol on short-term outcome of kidney transplantation by comparing two groups based on prescribing mannitol to donors.
In a randomized clinical trial, 60 kidney recipients were assigned in two groups (30 in each), except that in one group donors received mannitol.
They were studied with respect to age, gender, weight, blood urea nitrogen (BUN), creatinine (Cr), sodium (Na), potassium (K) and arterial blood gas (ABG) before and after surgery, and their pulse rate (PR) and blood pressure (BP) before, during and after surgery.
Their urine volume was assessed in the operation room and the first 24 h after surgery.
The short-term outcome, including BUN and Cr in the first 10 days after transplant, have been charted.
Both the case (mannitol-positive donor patient) and the control (mannitol negative) groups were the same regarding the results gained for pre- and post-operative parameters.
Follow-up assessments showed no significant differences in renal function.
Based on this, we conclude that mannitol administration to donors does not have a beneficial effect on the prognosis and short-term outcome of transplantation on recipients; therefore, we feel that it should not be advised for kidney donors.
American Psychological Association (APA)
Isfarayini, Hellieh Sadat& Nurai, Navid& Asgary, Majid& Hashimian, Muhammad Rida. 2014. The effect of mannitol administration to kidney donor on short-term outcomes of kidney transplantation. Saudi Journal of Kidney Diseases and Transplantation،Vol. 25, no. 6, pp.1154-1159.
https://search.emarefa.net/detail/BIM-431375
Modern Language Association (MLA)
Isfarayini, Hellieh Sadat…[et al.]. The effect of mannitol administration to kidney donor on short-term outcomes of kidney transplantation. Saudi Journal of Kidney Diseases and Transplantation Vol. 25, no. 6 (Dec. 2014), pp.1154-1159.
https://search.emarefa.net/detail/BIM-431375
American Medical Association (AMA)
Isfarayini, Hellieh Sadat& Nurai, Navid& Asgary, Majid& Hashimian, Muhammad Rida. The effect of mannitol administration to kidney donor on short-term outcomes of kidney transplantation. Saudi Journal of Kidney Diseases and Transplantation. 2014. Vol. 25, no. 6, pp.1154-1159.
https://search.emarefa.net/detail/BIM-431375
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1158-1159
Record ID
BIM-431375