Infection-Induced Vulnerability of Perinatal Brain Injury
Joint Authors
Source
Neurology Research International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
A growing body of evidence demonstrates that susceptibility and progression of both acute and chronic central nervous system disease in the newborn is closely associated with an innate immune response that can manifest from either direct infection and/or infection-triggered damage.
A common feature of many of these diseases is the systemic exposure of the neonate to bacterial infections that elicit brain inflammation.
In recent years, the importance of innate immune receptors in newborn brain injury, the so-called Toll-like receptors, has been demonstrated.
In this paper we will discuss how neonatal sepsis, with particular emphasis on Escherichia coli, coagulase-negative staphylococci, and group B streptococcal infections in preterm infants, and Toll-like receptor-mediated inflammation can increase the vulnerability of the newborn brain to injury.
American Psychological Association (APA)
Mallard, Carina& Wang, Xiaoyang. 2011. Infection-Induced Vulnerability of Perinatal Brain Injury. Neurology Research International،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-446435
Modern Language Association (MLA)
Mallard, Carina& Wang, Xiaoyang. Infection-Induced Vulnerability of Perinatal Brain Injury. Neurology Research International No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-446435
American Medical Association (AMA)
Mallard, Carina& Wang, Xiaoyang. Infection-Induced Vulnerability of Perinatal Brain Injury. Neurology Research International. 2011. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-446435
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-446435