“On Water” Sonochemical Multicomponent Synthesis of Novel Bioactive 1,1′-(Aryl)bis(2-(cyclohexylamino)-2-oxoethane-1,1-diyl) Di(alkanoates and benzoates)
Joint Authors
Mahmoodi, Nosrat O.
Azimi-Roshan, Abbas
Monfared, Azam
Shirini, Farhad
Mamaghani, Manouchehr
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
An expeditious, efficient, and ecofriendly ultrasound-promoted synthesis of a series of novel 1,1′-(aryl)bis(2-(cyclohexylamino)-2-oxoethane-1,1-diyl) di(alkanoate and benzoate) derivatives (6a–k), as useful building block candidates for natural products and drugs, is reported.
The target compounds were prepared by the reaction of alkyl or aryl carboxylic acid, various bisaldehydes and isocyanocyclohexane in water using one-pot isocyanide-based multicomponent approach.
This efficient protocol without using any catalyst furnished the products in short reaction times (4-5 min) and excellent yields (87–96%).
The antibacterial activity of the selected products was also examined.
Some products showed promising activities.
American Psychological Association (APA)
Mamaghani, Manouchehr& Mahmoodi, Nosrat O.& Shirini, Farhad& Azimi-Roshan, Abbas& Monfared, Azam. 2013. “On Water” Sonochemical Multicomponent Synthesis of Novel Bioactive 1,1′-(Aryl)bis(2-(cyclohexylamino)-2-oxoethane-1,1-diyl) Di(alkanoates and benzoates). Journal of Chemistry،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-447665
Modern Language Association (MLA)
Mamaghani, Manouchehr…[et al.]. “On Water” Sonochemical Multicomponent Synthesis of Novel Bioactive 1,1′-(Aryl)bis(2-(cyclohexylamino)-2-oxoethane-1,1-diyl) Di(alkanoates and benzoates). Journal of Chemistry No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-447665
American Medical Association (AMA)
Mamaghani, Manouchehr& Mahmoodi, Nosrat O.& Shirini, Farhad& Azimi-Roshan, Abbas& Monfared, Azam. “On Water” Sonochemical Multicomponent Synthesis of Novel Bioactive 1,1′-(Aryl)bis(2-(cyclohexylamino)-2-oxoethane-1,1-diyl) Di(alkanoates and benzoates). Journal of Chemistry. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-447665
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447665