Angiogenesis and Its Therapeutic Opportunities

Joint Authors

Yoo, So Young
Kwon, Sang Mo

Source

Mediators of Inflammation

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-07-28

Country of Publication

Egypt

No. of Pages

11

Main Subjects

Diseases

Abstract EN

Angiogenesis plays critical roles in human physiology that range from reproduction and fetal growth to wound healing and tissue repair.

The sophisticated multistep process is tightly regulated in a spatial and temporal manner by “on-off switch signals” between angiogenic factors, extracellular matrix components, and endothelial cells.

Uncontrolled angiogenesis may lead to several angiogenic disorders, including vascular insufficiency (myocardial or critical limb ischemia) and vascular overgrowth (hemangiomas, vascularized tumors, and retinopathies).

Thus, numerous therapeutic opportunities can be envisaged through the successful understanding and subsequent manipulation of angiogenesis.

Here, we review the clinical implications of angiogenesis and discuss pro- and antiangiogenic agents that offer potential therapy for cancer and other angiogenic diseases.

American Psychological Association (APA)

Yoo, So Young& Kwon, Sang Mo. 2013. Angiogenesis and Its Therapeutic Opportunities. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-447770

Modern Language Association (MLA)

Yoo, So Young& Kwon, Sang Mo. Angiogenesis and Its Therapeutic Opportunities. Mediators of Inflammation No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-447770

American Medical Association (AMA)

Yoo, So Young& Kwon, Sang Mo. Angiogenesis and Its Therapeutic Opportunities. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-447770

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-447770