Angiogenesis and Its Therapeutic Opportunities
Joint Authors
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-28
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Angiogenesis plays critical roles in human physiology that range from reproduction and fetal growth to wound healing and tissue repair.
The sophisticated multistep process is tightly regulated in a spatial and temporal manner by “on-off switch signals” between angiogenic factors, extracellular matrix components, and endothelial cells.
Uncontrolled angiogenesis may lead to several angiogenic disorders, including vascular insufficiency (myocardial or critical limb ischemia) and vascular overgrowth (hemangiomas, vascularized tumors, and retinopathies).
Thus, numerous therapeutic opportunities can be envisaged through the successful understanding and subsequent manipulation of angiogenesis.
Here, we review the clinical implications of angiogenesis and discuss pro- and antiangiogenic agents that offer potential therapy for cancer and other angiogenic diseases.
American Psychological Association (APA)
Yoo, So Young& Kwon, Sang Mo. 2013. Angiogenesis and Its Therapeutic Opportunities. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-447770
Modern Language Association (MLA)
Yoo, So Young& Kwon, Sang Mo. Angiogenesis and Its Therapeutic Opportunities. Mediators of Inflammation No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-447770
American Medical Association (AMA)
Yoo, So Young& Kwon, Sang Mo. Angiogenesis and Its Therapeutic Opportunities. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-447770
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-447770