Synthetic Biology : Tools to Design, Build, and Optimize Cellular Processes
Joint Authors
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-01-27
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The general central dogma frames the emergent properties of life, which make biology both necessary and difficult to engineer.
In a process engineering paradigm, each biological process stream and process unit is heavily influenced by regulatory interactions and interactions with the surrounding environment.
Synthetic biology is developing the tools and methods that will increase control over these interactions, eventually resulting in an integrative synthetic biology that will allow ground-up cellular optimization.
In this review, we attempt to contextualize the areas of synthetic biology into three tiers: (1) the process units and associated streams of the central dogma, (2) the intrinsic regulatory mechanisms, and (3) the extrinsic physical and chemical environment.
Efforts at each of these three tiers attempt to control cellular systems and take advantage of emerging tools and approaches.
Ultimately, it will be possible to integrate these approaches and realize the vision of integrative synthetic biology when cells are completely rewired for biotechnological goals.
This review will highlight progress towards this goal as well as areas requiring further research.
American Psychological Association (APA)
Young, Eric& Alper, Hal. 2010. Synthetic Biology : Tools to Design, Build, and Optimize Cellular Processes. Journal of Biomedicine and Biotechnology،Vol. 2010, no. 2010, pp.1-12.
https://search.emarefa.net/detail/BIM-448125
Modern Language Association (MLA)
Young, Eric& Alper, Hal. Synthetic Biology : Tools to Design, Build, and Optimize Cellular Processes. Journal of Biomedicine and Biotechnology No. 2010 (2010), pp.1-12.
https://search.emarefa.net/detail/BIM-448125
American Medical Association (AMA)
Young, Eric& Alper, Hal. Synthetic Biology : Tools to Design, Build, and Optimize Cellular Processes. Journal of Biomedicine and Biotechnology. 2010. Vol. 2010, no. 2010, pp.1-12.
https://search.emarefa.net/detail/BIM-448125
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448125