Prognostic Value of VEGF in Patients Submitted to Percutaneous Coronary Intervention
Joint Authors
Pinheiro, Teresa
Selas, Mafalda
Cruz Ferreira, Rui
Napoleão, Patrícia
Freixo, Cláudia
Ramos, Catarina
Mota Carmo, Miguel
Viegas Crespo, Ana Maria
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We examined the longitudinal changes of VEGF levels after percutaneous coronary intervention for predicting major adverse cardiac events (MACE) in coronary artery disease (CAD) patients.
VEGF was measured in 94 CAD patients’ serum before revascularization, 1-month and 1-year after.
Independently of clinical presentation, patients had lower VEGF concentration than a cohort of healthy subjects (median, IQ: 15.9, 9.0–264 pg/mL versus 419, 212–758 pg/mL; P<0.001) at baseline.
VEGF increased to 1-month (median, IQ: 276, 167–498 pg/mL; P<0.001) and remained steady to 1-year (median, IQ: 320, 173–497 pg/mL; P<0.001) approaching control levels.
Drug eluting stent apposition and previous medication intake produced a less steep VEGF evolution after intervention (P<0.05).
Baseline VEGF concentration <40.8 pg/mL conveyed increased risk for MACE in a 5-year follow-up.
Results reflect a positive role of VEGF in recovery and support its importance in CAD prognosis.
American Psychological Association (APA)
Ramos, Catarina& Napoleão, Patrícia& Selas, Mafalda& Freixo, Cláudia& Viegas Crespo, Ana Maria& Mota Carmo, Miguel…[et al.]. 2014. Prognostic Value of VEGF in Patients Submitted to Percutaneous Coronary Intervention. Disease Markers،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-448477
Modern Language Association (MLA)
Ramos, Catarina…[et al.]. Prognostic Value of VEGF in Patients Submitted to Percutaneous Coronary Intervention. Disease Markers No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-448477
American Medical Association (AMA)
Ramos, Catarina& Napoleão, Patrícia& Selas, Mafalda& Freixo, Cláudia& Viegas Crespo, Ana Maria& Mota Carmo, Miguel…[et al.]. Prognostic Value of VEGF in Patients Submitted to Percutaneous Coronary Intervention. Disease Markers. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-448477
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-448477