Eosinophil as a Protective Cell in S. aureus Ventilator-Associated Pneumonia
Joint Authors
Andaluz-Ojeda, David
Ortiz de Lejarazu, Raul
Eiros, Jose Maria
Almansa, Raquel
Justel, Mar
Rodriguez-Fernandez, Ana
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-03
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Cell counts of leukocytes subpopulations are demonstrating to have an important value in predicting outcome in severe infections.
We evaluated here the render of leukogram counts to predict outcome in patients with ventilator-associated pneumonia (VAP) caused by Staphylococcus aureus.
Data from patients admitted to the ICU of Hospital Clínico Universitario de Valladolid from 2006 to 2011 with diagnosis of VAP caused by S.
aureus were retrospectively collected for the study (n=44).
Leukocyte counts were collected at ICU admission and also at VAP diagnosis.
Our results showed that nonsurvivors had significant lower eosinophil counts at VAP diagnosis.
Multivariate Cox regression analysis performed by the Wald test for forward selection showed that eosinophil increments from ICU admission to VAP diagnosis and total eosinophil counts at VAP diagnosis were protective factors against mortality in the first 28 days following diagnosis: (HR [CI 95%], P): (0.996 [0.993–0.999], 0.010); (0.370 [0.180–0.750], 0.006).
Patients with eosinophil counts <30 cells/mm3 at diagnosis died earlier.
Eosinophil counts identified survivors: (AUROC [CI 95%], P): (0.701 [0.519–0.882], 0.042).
Eosinophil behaves as a protective cell in patients with VAP caused by S.
aureus.
American Psychological Association (APA)
Rodriguez-Fernandez, Ana& Andaluz-Ojeda, David& Almansa, Raquel& Justel, Mar& Eiros, Jose Maria& Ortiz de Lejarazu, Raul. 2013. Eosinophil as a Protective Cell in S. aureus Ventilator-Associated Pneumonia. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-450011
Modern Language Association (MLA)
Rodriguez-Fernandez, Ana…[et al.]. Eosinophil as a Protective Cell in S. aureus Ventilator-Associated Pneumonia. Mediators of Inflammation No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-450011
American Medical Association (AMA)
Rodriguez-Fernandez, Ana& Andaluz-Ojeda, David& Almansa, Raquel& Justel, Mar& Eiros, Jose Maria& Ortiz de Lejarazu, Raul. Eosinophil as a Protective Cell in S. aureus Ventilator-Associated Pneumonia. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-450011
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-450011