Validation Study Methods for Estimating Odds Ratio in 2×2×J Tables When Exposure is Misclassified
Joint Authors
Nouri, Bijan
Zare, Najaf
Ayatollahi, Seyyed Mohammad Taghi
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-23
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Misclassification of exposure variables in epidemiologic studies may lead to biased estimation of parameters and loss of power in statistical inferences.
In this paper, the inverse matrix method, as an efficient method of the correction of odds ratio for the misclassification of a binary exposure, was generalized to nondifferential misclassification and 2×2×J tables.
Methods.
Simple estimates for predictive values when misclassification is nondifferential are presented.
Using them, we estimated the corrected log odds ratio and its variance for 2×2×J tables, using the inverse matrix method.
A two-step weighted likelihood method was also developed.
Moreover, we compared the matrix and inverse matrix methods to the maximum likelihood (MLE) method using a simulation study.
Results.
In all situations, the inverse matrix method proved to be more efficient than the matrix method.
Matrix and inverse matrix methods for nondifferential situations are more efficient than differential misclassification.
Conclusions.
Although MLE is optimal among all of the methods, it is computationally difficult and requires programming.
On the other hand, the inverse matrix method with a simple closed-form presents acceptable efficiency.
American Psychological Association (APA)
Nouri, Bijan& Zare, Najaf& Ayatollahi, Seyyed Mohammad Taghi. 2013. Validation Study Methods for Estimating Odds Ratio in 2×2×J Tables When Exposure is Misclassified. Computational and Mathematical Methods in Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-451455
Modern Language Association (MLA)
Nouri, Bijan…[et al.]. Validation Study Methods for Estimating Odds Ratio in 2×2×J Tables When Exposure is Misclassified. Computational and Mathematical Methods in Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-451455
American Medical Association (AMA)
Nouri, Bijan& Zare, Najaf& Ayatollahi, Seyyed Mohammad Taghi. Validation Study Methods for Estimating Odds Ratio in 2×2×J Tables When Exposure is Misclassified. Computational and Mathematical Methods in Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-451455
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451455