Microwave-Assisted Synthesis, Characterization, Antimicrobial and Antioxidant Activity of Some New Isatin Derivatives
Joint Authors
Sarangapani, M.
Rajeshwar, Y.
Kiran, G.
Maneshwar, T.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-22
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
A series of β-Isatin aldehyde-N,N′-thiocarbohydrazone derivatives were synthesized and assayed for their in vitro antimicrobial and antioxidant activity.
The new compounds were characterized based on spectral (FT-IR, NMR, MS) analyses.
All the test compounds possessed a broad spectrum of activity having MIC values rangeing from 12.5 to 400 μg/ml against the tested microorganisms.
Among the compounds 3e, 3j and 3n show highest significant antimicrobial activity.
The free radical scavenging effects of the test compounds against stable free radical DPPH (α,α-diphenyl-β-picryl hydrazyl) and H2O2 were measured spectrophotometrically.
Compounds 3j, 3n, 3l, and 3e, respectively, had the most effective antioxidant activity against DPPH and H2O2 scavenging activity.
American Psychological Association (APA)
Kiran, G.& Maneshwar, T.& Rajeshwar, Y.& Sarangapani, M.. 2012. Microwave-Assisted Synthesis, Characterization, Antimicrobial and Antioxidant Activity of Some New Isatin Derivatives. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-453280
Modern Language Association (MLA)
Kiran, G.…[et al.]. Microwave-Assisted Synthesis, Characterization, Antimicrobial and Antioxidant Activity of Some New Isatin Derivatives. Journal of Chemistry No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-453280
American Medical Association (AMA)
Kiran, G.& Maneshwar, T.& Rajeshwar, Y.& Sarangapani, M.. Microwave-Assisted Synthesis, Characterization, Antimicrobial and Antioxidant Activity of Some New Isatin Derivatives. Journal of Chemistry. 2012. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-453280
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-453280