Xanthomatous Hypophysitis Mimicking a Pituitary Adenoma : Case Report and Review of the Literature
Joint Authors
Godano, Umberto
Aste, Laura
Bellinzona, Mattia
Farci, Graziella
Manieli, Cristina
Meleddu, Veronica
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-07-08
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Hypophysitis is an inflammatory disease of the pituitary gland that may mimic pituitary tumors clinically and radiologically.
Case Description.
We report a case of a xanthomatous hypophysitis initially diagnosed as pituitary adenoma.
A 31-year-old woman presented with headache, diabetes insipidus, and amenorrhea.
A head CT scan showed no intrasellar changes, while an MRI scan showed a sellar cystic mass.
An endocrinological work up revealed mild hypocortisolism and diabetes insipidus (DI).
Transsphenoidal surgery was performed.
The intraoperative histological examination suggested a pituitary adenoma.
The removed tissue showed central necrosis surrounded by accumulation of foamy cells and xanthomatous epithelioid cells.
The patient made an uneventful postoperative recovery, Nevertheless, DI persisted and the adenohypophysis hypofunction did not recover.
Conclusion.
We describe an unusual inflammatory lesion of the pituitary gland mimicking an adenoma.
A high level of clinical suspicion of inflammatory disorders is necessary for correct diagnosis and optimal management.
American Psychological Association (APA)
Aste, Laura& Bellinzona, Mattia& Meleddu, Veronica& Farci, Graziella& Manieli, Cristina& Godano, Umberto. 2010. Xanthomatous Hypophysitis Mimicking a Pituitary Adenoma : Case Report and Review of the Literature. Journal of Oncology،Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-453595
Modern Language Association (MLA)
Aste, Laura…[et al.]. Xanthomatous Hypophysitis Mimicking a Pituitary Adenoma : Case Report and Review of the Literature. Journal of Oncology No. 2010 (2010), pp.1-5.
https://search.emarefa.net/detail/BIM-453595
American Medical Association (AMA)
Aste, Laura& Bellinzona, Mattia& Meleddu, Veronica& Farci, Graziella& Manieli, Cristina& Godano, Umberto. Xanthomatous Hypophysitis Mimicking a Pituitary Adenoma : Case Report and Review of the Literature. Journal of Oncology. 2010. Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-453595
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-453595