Role of Phosphorylation in the Control of Clathrin-Mediated Internalization of GPCR
Joint Authors
Delom, Frederic
Fessart, Delphine
Source
International Journal of Cell Biology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-07
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
The process by which G protein-coupled receptors (GPCRs) are internalized through the clathrin-coated vesicles involves interactions of multifunctional adaptor proteins.
These interactions are tightly controlled by phosphorylation and dephosphorylation mechanisms resulting in the regulation of receptor endocytosis.
However, the identities of the kinases involved in this process remained largely unknown until recently.
This paper discusses advances in our knowledge of the important role played by protein phosphorylation in the regulation of the endocytic machinery and how phosphorylation controls the coated vesicle cycle.
American Psychological Association (APA)
Delom, Frederic& Fessart, Delphine. 2011. Role of Phosphorylation in the Control of Clathrin-Mediated Internalization of GPCR. International Journal of Cell Biology،Vol. 2011, no. 2011, pp.1-14.
https://search.emarefa.net/detail/BIM-457047
Modern Language Association (MLA)
Delom, Frederic& Fessart, Delphine. Role of Phosphorylation in the Control of Clathrin-Mediated Internalization of GPCR. International Journal of Cell Biology No. 2011 (2011), pp.1-14.
https://search.emarefa.net/detail/BIM-457047
American Medical Association (AMA)
Delom, Frederic& Fessart, Delphine. Role of Phosphorylation in the Control of Clathrin-Mediated Internalization of GPCR. International Journal of Cell Biology. 2011. Vol. 2011, no. 2011, pp.1-14.
https://search.emarefa.net/detail/BIM-457047
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-457047