The Correlation between Chronic Periodontitis and Oral Cancer
Joint Authors
Hansen, Torsten
Krüger, Maximilian
Kasaj, Adrian
Moergel, Maximilian
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-08
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Infections are increasingly considered as potential trigger for carcinogenesis apart from risk factors like alcohol and tobacco.
The discussion about human papilloma virus (HPV) in oral squamous cell carcinoma (OSCC) points at a general role of infection for the development of oral carcinomas.
Furthermore, first studies describe a correlation between chronic periodontitis and OSCC, thus, characterizing chronic inflammation as being a possible trigger for OSCC.
In front of this background, we present four well-documented clinical cases.
All patients showed a significant anatomical relation between OSCC and clinical signs of chronic periodontitis.
The interindividual differences of the clinical findings lead to different theoretical concepts: two with coincidental appearance of OSCC and chronic periodontitis and two with possible de novo development of OSCC triggered by chronic inflammation.
We conclude that the activation of different inflammatory cascades by chronic periodontitis negatively affects mucosa and bone.
Furthermore, the inflammatory response has the potential to activate carcinogenesis.
Apart from a mere coincidental occurrence, two out of four patients give first clinical hints for a model wherein chronic periodontitis represents a potential risk factor for the development of OSCC.
American Psychological Association (APA)
Krüger, Maximilian& Hansen, Torsten& Kasaj, Adrian& Moergel, Maximilian. 2013. The Correlation between Chronic Periodontitis and Oral Cancer. Case Reports in Dentistry،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-458456
Modern Language Association (MLA)
Krüger, Maximilian…[et al.]. The Correlation between Chronic Periodontitis and Oral Cancer. Case Reports in Dentistry No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-458456
American Medical Association (AMA)
Krüger, Maximilian& Hansen, Torsten& Kasaj, Adrian& Moergel, Maximilian. The Correlation between Chronic Periodontitis and Oral Cancer. Case Reports in Dentistry. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-458456
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458456