Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene
Author
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-09
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Zinc(II) halides and perchlorate react with 1,4-bis(benzimidazol-2-yl)benzene (L) in 1 : 2 molar ratio in n-butanol/2-methoxy ethanol (10 mL) at refluxing temperature to produce white/pale yellow-colored complexes of the formulae [ZnCl2L]H2O, [ZnBr2L]3H2O, and [Zn(OClO3)2L]HOCH2CH2CH2CH3.
Zinc(II) iodide also reacts with L in 1 : 2 molar ratio in n-butanol (HOCH2CH2CH2CH3) to yield white-colored complex of the formula [ZnL2(OCH2CH2CH2CH3)2].
The complexes were characterized by elemental analysis, molar conductance measurements, thermal analysis, and IR, 1H-, 13C-NMR spectral studies.
The complexes showed significant anthelmintic activity.
The minimum energy configuration has been obtained for the zinc complexes using molecular modeling Pro Plus; a tool developed by ChemSW, inc, USA.
American Psychological Association (APA)
Krishnamurthy, G.. 2012. Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-458711
Modern Language Association (MLA)
Krishnamurthy, G.. Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene. Journal of Chemistry No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-458711
American Medical Association (AMA)
Krishnamurthy, G.. Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene. Journal of Chemistry. 2012. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-458711
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458711