Lessons Learned from a Case of Abdominal Aortic Aneurysm Accompanied by Unstable Coagulopathy
Joint Authors
Hosaka, Akihiro
Hoshina, Katsuyuki
Okamoto, Hiroyuki
Kaneko, Makoto
Shigematsu, Kunihiro
Miyata, Tetsuro
Source
Case Reports in Vascular Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-09
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Preoperative examination for abdominal aortic aneurysms (AAAs) occasionally reveals an abnormal decrease in coagulation factors and thrombocytopenia, fulfilling the criteria for disseminated intravascular coagulation (DIC).
Treatment of the underlying disorder is indispensable for alleviating DIC.
We report an uncommon case of a patient with AAA and DIC who showed prolonged thrombocytopenia despite successful treatment of AAA and temporary recovery of coagulation factors.
A 70-year-old man presented with AAA and shaggy aorta accompanied by DIC and underwent aneurysmectomy.
Combined preoperative use of nafamostat mesilate and recombinant human soluble thrombomodulin was effective in controlling DIC.
Although recovery of coagulation factors was observed after surgery, the thrombocytopenia continued throughout the postoperative course and was refractory to platelet transfusion.
Because HPA antibody and PA-IgG were present, a trial administration of γ-globulin was performed; this resulted in rapid improvement of thrombocytopenia.
Although DIC recurred again 2 weeks thereafter, coagulation factors subsequently recovered without any medication.
American Psychological Association (APA)
Hoshina, Katsuyuki& Kaneko, Makoto& Hosaka, Akihiro& Okamoto, Hiroyuki& Shigematsu, Kunihiro& Miyata, Tetsuro. 2012. Lessons Learned from a Case of Abdominal Aortic Aneurysm Accompanied by Unstable Coagulopathy. Case Reports in Vascular Medicine،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-458771
Modern Language Association (MLA)
Hoshina, Katsuyuki…[et al.]. Lessons Learned from a Case of Abdominal Aortic Aneurysm Accompanied by Unstable Coagulopathy. Case Reports in Vascular Medicine No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-458771
American Medical Association (AMA)
Hoshina, Katsuyuki& Kaneko, Makoto& Hosaka, Akihiro& Okamoto, Hiroyuki& Shigematsu, Kunihiro& Miyata, Tetsuro. Lessons Learned from a Case of Abdominal Aortic Aneurysm Accompanied by Unstable Coagulopathy. Case Reports in Vascular Medicine. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-458771
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-458771