PCR-SSCP Variation of IGF1 and PIT1 Genes and Their Association with Estimated Breeding Values of Growth Traits in Makooei Sheep
Joint Authors
Hajihosseinlo, Abbas
Ajdary, Marziyeh
Negahdary, Masoud
Source
Genetics Research International
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Molecular biology techniques genetic improvement by facilitating identification, mapping and analysis of polymorphism of genes by encoding proteins that act on metabolic pathways involved in economically interesting traits.
This use of genetic markers can aid identification of those animals with the highest breeding values in sheep.
On the basis of sheep genome mapping, information was examined on the ovine IGF1 and PIT1 genes as a possible genetic marker for growth traits in sheep.
The current study was designed to estimate the frequencies of putative IGF-1 and PIT-1 genes SNPs and investigate associations with calculated EBVs of growth traits in Makooei sheep.
PCR-SSCP analysis of the exon1 of IGF-I gene and include a part of intron2, exon3 and a part of intron3 and PIT-1 gene revealed the following banding patterns; three (AA, AG, GG) and four AA (p1), AB (p2), CC (p3), CD (p4), banding patterns respectively.
Results from this study demonstrated higher performance of AA animals in BW and GBW, and AG animal in WW and W6 that may be related to the role of IGF-1 at the pre-puberty and puberty stages.
Also higher performance of p3 animals in W9, YW and GSN, and p1 animal in GNY may be related to the PIT-1 role in post-puberty.
American Psychological Association (APA)
Negahdary, Masoud& Hajihosseinlo, Abbas& Ajdary, Marziyeh. 2013. PCR-SSCP Variation of IGF1 and PIT1 Genes and Their Association with Estimated Breeding Values of Growth Traits in Makooei Sheep. Genetics Research International،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-459277
Modern Language Association (MLA)
Negahdary, Masoud…[et al.]. PCR-SSCP Variation of IGF1 and PIT1 Genes and Their Association with Estimated Breeding Values of Growth Traits in Makooei Sheep. Genetics Research International No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-459277
American Medical Association (AMA)
Negahdary, Masoud& Hajihosseinlo, Abbas& Ajdary, Marziyeh. PCR-SSCP Variation of IGF1 and PIT1 Genes and Their Association with Estimated Breeding Values of Growth Traits in Makooei Sheep. Genetics Research International. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-459277
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-459277