Towards In Vivo Imaging of Cancer Sialylation
Joint Authors
Salinas-Marin, Roberta
Martinez-Duncker, Carlos
Martínez-Duncker, Iván
Source
International Journal of Molecular Imaging
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-19
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
In vivo assessment of tumor glucose catabolism by positron emission tomography (PET) has become a highly valued study in the medical management of cancer.
Emerging technologies offer the potential to evaluate in vivo another aspect of cancer carbohydrate metabolism related to the increased anabolic use of monosaccharides like sialic acid (Sia).
Sia is used for the synthesis of sialylated oligosaccharides in the cell surface that in cancer cells are overexpressed and positively associated to malignancy and worse prognosis because of their role in invasion and metastasis.
This paper addresses the key points of the different strategies that have been developed to image Sia expression in vivo and the perspectives to translate it from the bench to the bedside where it would offer the clinician highly valued complementary information on cancer carbohydrate metabolism that is currently unavailable in vivo.
American Psychological Association (APA)
Martínez-Duncker, Iván& Salinas-Marin, Roberta& Martinez-Duncker, Carlos. 2011. Towards In Vivo Imaging of Cancer Sialylation. International Journal of Molecular Imaging،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-460193
Modern Language Association (MLA)
Martínez-Duncker, Iván…[et al.]. Towards In Vivo Imaging of Cancer Sialylation. International Journal of Molecular Imaging No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-460193
American Medical Association (AMA)
Martínez-Duncker, Iván& Salinas-Marin, Roberta& Martinez-Duncker, Carlos. Towards In Vivo Imaging of Cancer Sialylation. International Journal of Molecular Imaging. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-460193
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460193