Towards In Vivo Imaging of Cancer Sialylation

Joint Authors

Salinas-Marin, Roberta
Martinez-Duncker, Carlos
Martínez-Duncker, Iván

Source

International Journal of Molecular Imaging

Issue

Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-09-19

Country of Publication

Egypt

No. of Pages

10

Main Subjects

Medicine

Abstract EN

In vivo assessment of tumor glucose catabolism by positron emission tomography (PET) has become a highly valued study in the medical management of cancer.

Emerging technologies offer the potential to evaluate in vivo another aspect of cancer carbohydrate metabolism related to the increased anabolic use of monosaccharides like sialic acid (Sia).

Sia is used for the synthesis of sialylated oligosaccharides in the cell surface that in cancer cells are overexpressed and positively associated to malignancy and worse prognosis because of their role in invasion and metastasis.

This paper addresses the key points of the different strategies that have been developed to image Sia expression in vivo and the perspectives to translate it from the bench to the bedside where it would offer the clinician highly valued complementary information on cancer carbohydrate metabolism that is currently unavailable in vivo.

American Psychological Association (APA)

Martínez-Duncker, Iván& Salinas-Marin, Roberta& Martinez-Duncker, Carlos. 2011. Towards In Vivo Imaging of Cancer Sialylation. International Journal of Molecular Imaging،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-460193

Modern Language Association (MLA)

Martínez-Duncker, Iván…[et al.]. Towards In Vivo Imaging of Cancer Sialylation. International Journal of Molecular Imaging No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-460193

American Medical Association (AMA)

Martínez-Duncker, Iván& Salinas-Marin, Roberta& Martinez-Duncker, Carlos. Towards In Vivo Imaging of Cancer Sialylation. International Journal of Molecular Imaging. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-460193

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-460193