Vagus Nerve through α7 nAChR Modulates Lung Infection and Inflammation : Models, Cells, and Signals
Joint Authors
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-20, 20 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-20
Country of Publication
Egypt
No. of Pages
20
Main Subjects
Abstract EN
Cholinergic anti-inflammatory pathway (CAP) bridges immune and nervous systems and plays pleiotropic roles in modulating inflammation in animal models by targeting different immune, proinflammatory, epithelial, endothelial, stem, and progenitor cells and signaling pathways.
Acute lung injury (ALI) is a devastating inflammatory disease.
It is pathogenically heterogeneous and involves many cells and signaling pathways.
Here, we emphasized the research regarding the modulatory effects of CAP on animal models, cell population, and signaling pathways that involved in the pathogenesis of ALI.
By comparing the differential effects of CAP on systemic and pulmonary inflammation, we postulated that a pulmonary parasympathetic inflammatory reflex is formed to sense and respond to pathogens in the lung.
Work targeting the formation and function of pulmonary parasympathetic inflammatory reflex would extend our understanding of how vagus nerve senses, recognizes, and fights with pathogens and inflammatory responses.
American Psychological Association (APA)
Wu, Haiya& Li, Ling& Su, Xiao. 2014. Vagus Nerve through α7 nAChR Modulates Lung Infection and Inflammation : Models, Cells, and Signals. BioMed Research International،Vol. 2014, no. 2014, pp.1-20.
https://search.emarefa.net/detail/BIM-460196
Modern Language Association (MLA)
Wu, Haiya…[et al.]. Vagus Nerve through α7 nAChR Modulates Lung Infection and Inflammation : Models, Cells, and Signals. BioMed Research International No. 2014 (2014), pp.1-20.
https://search.emarefa.net/detail/BIM-460196
American Medical Association (AMA)
Wu, Haiya& Li, Ling& Su, Xiao. Vagus Nerve through α7 nAChR Modulates Lung Infection and Inflammation : Models, Cells, and Signals. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-20.
https://search.emarefa.net/detail/BIM-460196
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460196