New Delivery Systems for Local Anaesthetics—Part 2
Author
Source
Anesthesiology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-08
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Part 2 of this paper deals with the techniques for drug delivery of topical and injectable local anaesthetics.
The various routes of local anaesthetic delivery (epidural, peripheral, wound catheters, intra-nasal, intra-vesical, intra-articular, intra-osseous) are explored.
To enhance transdermal local anaesthetic permeation, additional methods to the use of an eutectic mixture of local anaesthetics and the use of controlled heat can be used.
These methods include iontophoresis, electroporation, sonophoresis, and magnetophoresis.
The potential clinical uses of topical local anaesthetics are elucidated.
Iontophoresis, the active transportation of a drug into the skin using a constant low-voltage direct current is discussed.
It is desirable to prolong local anaesthetic blockade by extending its sensory component only.
The optimal release and safety of the encapsulated local anaesthetic agents still need to be determined.
The use of different delivery systems should provide the clinician with both an extended range and choice in the degree of prolongation of action of each agent.
American Psychological Association (APA)
Shipton, Edward A.. 2011. New Delivery Systems for Local Anaesthetics—Part 2. Anesthesiology Research and Practice،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-460654
Modern Language Association (MLA)
Shipton, Edward A.. New Delivery Systems for Local Anaesthetics—Part 2. Anesthesiology Research and Practice No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-460654
American Medical Association (AMA)
Shipton, Edward A.. New Delivery Systems for Local Anaesthetics—Part 2. Anesthesiology Research and Practice. 2011. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-460654
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460654