The Ethanol Extract of Osmanthus fragrans Flowers Reduces Oxidative Stress and Allergic Airway Inflammation in an Animal Model
Joint Authors
Hung, Tsung-Jen
Hung, Chien-Ya
Ka, Shuk-Man
Wang, Jing-Yao
Ye, Yi-Ling
Shi, Li-Shian
Huang, Fu-Long
Tsai, Yu-Cheng
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-10
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The Osmanthus fragrans flower, a popular herb in Eastern countries, contains several antioxidant compounds.
Ben Cao Gang Mu, traditional Chinese medical literature, describes the usefulness of these flowers for phlegm and stasis reduction, arrest of dysentery with blood in the bowel, and stomachache and diarrhea treatment.
However, modern evidence regarding the therapeutic efficacy of these flowers is limited.
This study was aimed at assessing the antioxidative effects of the ethanol extract of O.
fragrans flowers (OFE) in vivo and evaluating its antioxidant maintenance and therapeutic effect on an allergic airway inflammation in mice.
After OFE’s oral administration to mice, the values obtained in the oxygen radical absorbance capacity assay as well as the glutathione concentration in the lungs and spleens of mice increased while thiobarbituric acid reactive substances decreased significantly, indicating OFE’s significant in vivo antioxidant activity.
OFE was also therapeutically efficacious in a mouse model of ovalbumin-induced allergic airway inflammation.
Orally administered OFE suppressed ovalbumin-specific IgE production and inflammatory cell infiltration in the lung.
Moreover, the antioxidative state of the mice improved.
Thus, our findings confirm the ability of the O.
fragrans flowers to reduce phlegm and suggest that OFE may be useful as an antiallergic agent.
American Psychological Association (APA)
Hung, Chien-Ya& Huang, Fu-Long& Shi, Li-Shian& Ka, Shuk-Man& Wang, Jing-Yao& Tsai, Yu-Cheng…[et al.]. 2013. The Ethanol Extract of Osmanthus fragrans Flowers Reduces Oxidative Stress and Allergic Airway Inflammation in an Animal Model. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-461851
Modern Language Association (MLA)
Hung, Chien-Ya…[et al.]. The Ethanol Extract of Osmanthus fragrans Flowers Reduces Oxidative Stress and Allergic Airway Inflammation in an Animal Model. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-461851
American Medical Association (AMA)
Hung, Chien-Ya& Huang, Fu-Long& Shi, Li-Shian& Ka, Shuk-Man& Wang, Jing-Yao& Tsai, Yu-Cheng…[et al.]. The Ethanol Extract of Osmanthus fragrans Flowers Reduces Oxidative Stress and Allergic Airway Inflammation in an Animal Model. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-461851
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-461851