Recurrent and Progressive Abdominal Pain and Enteritis in a Japanese Patient with Paroxysmal Nocturnal Hemoglobinuria

Joint Authors

Hino, Akihisa
Yamashita, Yukiko
Yamaguchi, Mitsuhiro
Azenishi, Yasuhiko

Source

Case Reports in Hematology

Issue

Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2014-01-27

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Diseases

Abstract EN

This case report describes a young male patient with recurrent abdominal pain persisting for more than 16 months.

Clinical investigations showed signs of inflammation and pancytopenia.

A diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) was made 9 months after the onset of the abdominal pain, following endoscopic examinations that revealed evidence of a previously unknown hemorrhage.

Regular monitoring indicated that the abdominal pain was associated with elevations in lactate dehydrogenase, C-reactive proteins, and D-dimer levels.

The patient started treatment with the complement inhibitor eculizumab shortly after it was approved for use in Japanese PNH patients with hemolysis.

Resolution of the abdominal pain and normalization of clinical parameters were noted within 3 weeks from treatment initiation.

American Psychological Association (APA)

Hino, Akihisa& Yamashita, Yukiko& Yamaguchi, Mitsuhiro& Azenishi, Yasuhiko. 2014. Recurrent and Progressive Abdominal Pain and Enteritis in a Japanese Patient with Paroxysmal Nocturnal Hemoglobinuria. Case Reports in Hematology،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-462488

Modern Language Association (MLA)

Hino, Akihisa…[et al.]. Recurrent and Progressive Abdominal Pain and Enteritis in a Japanese Patient with Paroxysmal Nocturnal Hemoglobinuria. Case Reports in Hematology No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-462488

American Medical Association (AMA)

Hino, Akihisa& Yamashita, Yukiko& Yamaguchi, Mitsuhiro& Azenishi, Yasuhiko. Recurrent and Progressive Abdominal Pain and Enteritis in a Japanese Patient with Paroxysmal Nocturnal Hemoglobinuria. Case Reports in Hematology. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-462488

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-462488