Recurrent and Progressive Abdominal Pain and Enteritis in a Japanese Patient with Paroxysmal Nocturnal Hemoglobinuria
Joint Authors
Hino, Akihisa
Yamashita, Yukiko
Yamaguchi, Mitsuhiro
Azenishi, Yasuhiko
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-27
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
This case report describes a young male patient with recurrent abdominal pain persisting for more than 16 months.
Clinical investigations showed signs of inflammation and pancytopenia.
A diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) was made 9 months after the onset of the abdominal pain, following endoscopic examinations that revealed evidence of a previously unknown hemorrhage.
Regular monitoring indicated that the abdominal pain was associated with elevations in lactate dehydrogenase, C-reactive proteins, and D-dimer levels.
The patient started treatment with the complement inhibitor eculizumab shortly after it was approved for use in Japanese PNH patients with hemolysis.
Resolution of the abdominal pain and normalization of clinical parameters were noted within 3 weeks from treatment initiation.
American Psychological Association (APA)
Hino, Akihisa& Yamashita, Yukiko& Yamaguchi, Mitsuhiro& Azenishi, Yasuhiko. 2014. Recurrent and Progressive Abdominal Pain and Enteritis in a Japanese Patient with Paroxysmal Nocturnal Hemoglobinuria. Case Reports in Hematology،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-462488
Modern Language Association (MLA)
Hino, Akihisa…[et al.]. Recurrent and Progressive Abdominal Pain and Enteritis in a Japanese Patient with Paroxysmal Nocturnal Hemoglobinuria. Case Reports in Hematology No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-462488
American Medical Association (AMA)
Hino, Akihisa& Yamashita, Yukiko& Yamaguchi, Mitsuhiro& Azenishi, Yasuhiko. Recurrent and Progressive Abdominal Pain and Enteritis in a Japanese Patient with Paroxysmal Nocturnal Hemoglobinuria. Case Reports in Hematology. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-462488
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-462488