Thigmotropism of Malignant Melanoma Cells
Joint Authors
Quatresooz, Pascale
Piérard, Gérald E.
Noël, Fanchon
Piérard-Franchimont, Claudine
Source
Dermatology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-17
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
During malignant melanoma (MM) progression including incipient metastasis, neoplastic cells follow some specific migration paths inside the skin.
In particular, they progress along the dermoepidermal basement membrane, the hair follicles, the sweat gland apparatus, nerves, and the near perivascular space.
These features evoke the thigmotropism phenomenon defined as a contact-sensing growth of cells.
This process is likely connected to modulation in cell tensegrity (control of the cell shape).
These specifically located paucicellular aggregates of MM cells do not appear to be involved in the tumorigenic growth phase, but rather they participate in the so-called “accretive” growth model.
These MM cell collections are often part of the primary neoplasm, but they may, however, correspond to MM micrometastases and predict further local overt metastasis spread.
American Psychological Association (APA)
Quatresooz, Pascale& Piérard-Franchimont, Claudine& Noël, Fanchon& Piérard, Gérald E.. 2011. Thigmotropism of Malignant Melanoma Cells. Dermatology Research and Practice،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-466016
Modern Language Association (MLA)
Quatresooz, Pascale…[et al.]. Thigmotropism of Malignant Melanoma Cells. Dermatology Research and Practice No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-466016
American Medical Association (AMA)
Quatresooz, Pascale& Piérard-Franchimont, Claudine& Noël, Fanchon& Piérard, Gérald E.. Thigmotropism of Malignant Melanoma Cells. Dermatology Research and Practice. 2011. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-466016
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466016