Gastro-Oesophageal Reflux in Noncystic Fibrosis Bronchiectasis
Joint Authors
Denehy, Linda
Lee, Annemarie L.
Button, Brenda M.
Wilson, John W.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-10
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The clinical presentation of noncystic fibrosis bronchiectasis may be complicated by concomitant conditions, including gastro-oesophageal reflux (GOR).
Increased acidic GOR is principally caused by gastro-oesophageal junction incompetence and may arise from lower oesophageal sphincter hypotension, including transient relaxations, hiatus hernia, and oesophageal dysmotility.
Specific pathophysiological features which are characteristic of respiratory diseases including coughing may further increase the risk of GOR in bronchiectasis.
Reflux may impact on lung disease severity by two mechanisms, reflex bronchoconstriction and pulmonary microaspiration.
Symptomatic and clinically silent reflux has been detected in bronchiectasis, with the prevalence of 26 to 75%.
The cause and effect relationship has not been established, but preliminary reports suggest that GOR may influence the severity of bronchiectasis.
Further studies examining the implications of GOR in this condition, including its effect across the disease spectrum using a combination of diagnostic tools, will clarify the clinical significance of this comorbidity.
American Psychological Association (APA)
Lee, Annemarie L.& Button, Brenda M.& Denehy, Linda& Wilson, John W.. 2011. Gastro-Oesophageal Reflux in Noncystic Fibrosis Bronchiectasis. Pulmonary Medicine،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-468734
Modern Language Association (MLA)
Lee, Annemarie L.…[et al.]. Gastro-Oesophageal Reflux in Noncystic Fibrosis Bronchiectasis. Pulmonary Medicine No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-468734
American Medical Association (AMA)
Lee, Annemarie L.& Button, Brenda M.& Denehy, Linda& Wilson, John W.. Gastro-Oesophageal Reflux in Noncystic Fibrosis Bronchiectasis. Pulmonary Medicine. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-468734
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468734