Extramammary Paget’s Disease : 20 Years of Experience in Chinese Population
Joint Authors
Li, George Kam Hop
Chow, Velda Ling Yu
Chung, Joseph Hon Ping
Chan, Jimmy Yu-Wai
Source
International Journal of Surgical Oncology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-28
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
To examine the results of treatment of Extramammary Paget’s disease (EMPD) in ethnic Chinese.
Method.
Between 1990 and 2010, patients treated for EMPD were reviewed.
Data were analyzed retrospectively.
Results.
Forty-eight patients were treated by surgical resection.
Local recurrence rate was 14.6%.
The postresection defects were repaired by primary closure (8.3%), partial thickness skin graft (72.9%), or local/regional flaps (18.8%).
Dermal invasion was found in 9 patients (18.8%).
Seven patients (14.6%) developed regional lymph node metastasis (concurrent with surgery, n=1; subsequent to surgery, n=6), and 3 patients (6.3%) had systemic metastasis after surgery.
The presence of dermal invasion was associated with significantly higher incidence of regional lymph nodes and systemic metastasis.
The incidence of associated internal malignancy was 8.3%.
Conclusion.
The mainstay of treatment for EMPD is surgery.
Pathological dermal invasion increases the chance of regional lymph node as well as systemic metastasis.
The association with internal malignancy warrants preoperative endoscopic examination in all patients.
American Psychological Association (APA)
Chan, Jimmy Yu-Wai& Li, George Kam Hop& Chung, Joseph Hon Ping& Chow, Velda Ling Yu. 2012. Extramammary Paget’s Disease : 20 Years of Experience in Chinese Population. International Journal of Surgical Oncology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-470449
Modern Language Association (MLA)
Chan, Jimmy Yu-Wai…[et al.]. Extramammary Paget’s Disease : 20 Years of Experience in Chinese Population. International Journal of Surgical Oncology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-470449
American Medical Association (AMA)
Chan, Jimmy Yu-Wai& Li, George Kam Hop& Chung, Joseph Hon Ping& Chow, Velda Ling Yu. Extramammary Paget’s Disease : 20 Years of Experience in Chinese Population. International Journal of Surgical Oncology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-470449
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-470449