MicroRNA Roles in the NF-κB Signaling Pathway during Viral Infections

Abstract EN

NF-κB signaling network is a crucial component of innate immunity.

miRNAs are a subtype of small noncoding RNAs, involved in regulation of gene expression at the posttranscriptional level.

Increasing evidence has emerged that miRNAs play an important role in regulation of NF-κB signaling pathway during viral infections.

Both host and viral miRNAs are attributed to modulation of NF-κB activity, thus affecting viral infection and clearance.

Understandings of the mechanisms of these miRNAs will open a direction for development of novel antivirus drugs.