Alternative Cell Death Pathways and Cell Metabolism

Author

Fulda, Simone

Source

International Journal of Cell Biology

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-01-21

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Biology

Abstract EN

While necroptosis has for long been viewed as an accidental mode of cell death triggered by physical or chemical damage, it has become clear over the last years that necroptosis can also represent a programmed form of cell death in mammalian cells.

Key discoveries in the field of cell death research, including the identification of critical components of the necroptotic machinery, led to a revised concept of cell death signaling programs.

Several regulatory check and balances are in place in order to ensure that necroptosis is tightly controlled according to environmental cues and cellular needs.

This network of regulatory mechanisms includes metabolic pathways, especially those linked to mitochondrial signaling events.

A better understanding of these signal transduction mechanisms will likely contribute to open new avenues to exploit our knowledge on the regulation of necroptosis signaling for therapeutic application in the treatment of human diseases.

American Psychological Association (APA)

Fulda, Simone. 2013. Alternative Cell Death Pathways and Cell Metabolism. International Journal of Cell Biology،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-473584

Modern Language Association (MLA)

Fulda, Simone. Alternative Cell Death Pathways and Cell Metabolism. International Journal of Cell Biology No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-473584

American Medical Association (AMA)

Fulda, Simone. Alternative Cell Death Pathways and Cell Metabolism. International Journal of Cell Biology. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-473584

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-473584