![](/images/graphics-bg.png)
Uterine Carcinosarcomas (Malignant Mixed Müllerian Tumours) : A Review with Special Emphasis on the Controversies in Management
Joint Authors
Senger, Jenna-Lynn
Kanthan, Rani
Source
Obstetrics and Gynecology International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-05
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Uterine carcinosarcomas (MMMT—malignant mixed Müllerian tumours) are highly aggressive, rare, biphasic tumours composed of epithelial and mesenchymal elements believed to arise from a monoclonal origin.
While hysterectomy with bilateral salpingo-oophorectomy remains the mainstay treatment, high rates of recurrence and metastases suggest a need for lymphadenectomy and postoperative adjuvant treatment.
There are no established consensus guidelines for therapeutic patient management.
Though well recognized that it improves locoregional control, the role of radiation in improving overall survival outcomes remains undecided.
Although various combinations of chemotherapy have been explored, an optimal therapeutic modality is yet to be determined.
As overall survival rates have not improved in thirty years, it is suggested that targeted chemotherapy and/or a multimodality approach may yield better outcomes.
This paper provides a summary of the aetiopathogenesis of carcinosarcomas (MMMT) limited to the uterus with special emphasis on the controversies in the management of these patients.
American Psychological Association (APA)
Kanthan, Rani& Senger, Jenna-Lynn. 2011. Uterine Carcinosarcomas (Malignant Mixed Müllerian Tumours) : A Review with Special Emphasis on the Controversies in Management. Obstetrics and Gynecology International،Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-474090
Modern Language Association (MLA)
Kanthan, Rani& Senger, Jenna-Lynn. Uterine Carcinosarcomas (Malignant Mixed Müllerian Tumours) : A Review with Special Emphasis on the Controversies in Management. Obstetrics and Gynecology International No. 2011 (2011), pp.1-13.
https://search.emarefa.net/detail/BIM-474090
American Medical Association (AMA)
Kanthan, Rani& Senger, Jenna-Lynn. Uterine Carcinosarcomas (Malignant Mixed Müllerian Tumours) : A Review with Special Emphasis on the Controversies in Management. Obstetrics and Gynecology International. 2011. Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-474090
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-474090