The Neglected Significance of “Antioxidative Stress”
Joint Authors
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-08
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Oxidative stress arises when there is a marked imbalance between the production and removal of reactive oxygen species (ROS) in favor of the prooxidant balance, leading to potential oxidative damage.
ROSs were considered traditionally to be only a toxic byproduct of aerobic metabolism.
However, recently, it has become apparent that ROS might control many different physiological processes such as induction of stress response, pathogen defense, and systemic signaling.
Thus, the imbalance of the increased antioxidant potential, the so-called antioxidative stress, should be as dangerous as well.
Here, we synthesize increasing evidence on “antioxidative stress-induced” beneficial versus harmful roles on health, disease, and aging processes.
Oxidative stress is not necessarily an un-wanted situation, since its consequences may be beneficial for many physiological reactions in cells.
On the other hand, there are potentially harmful effects of “antioxidative stress,” especially in the cases of overconsumption of synthetic antioxidants.
Antioxidants can neutralize ROS and decrease oxidative stress; however, this is not always beneficial in regard to disease formation or progression (of, e.g., cancer) or for delaying aging.
American Psychological Association (APA)
Poljsak, Borut& Milisav, Irina. 2012. The Neglected Significance of “Antioxidative Stress”. Oxidative Medicine and Cellular Longevity،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-474947
Modern Language Association (MLA)
Poljsak, Borut& Milisav, Irina. The Neglected Significance of “Antioxidative Stress”. Oxidative Medicine and Cellular Longevity No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-474947
American Medical Association (AMA)
Poljsak, Borut& Milisav, Irina. The Neglected Significance of “Antioxidative Stress”. Oxidative Medicine and Cellular Longevity. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-474947
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-474947