Improving Blood Pressure Control in Patients with Diabetes Mellitus and High Cardiovascular Risk
Joint Authors
Lloyd, Suzanne M.
Meredith, Peter A.
Elliott, Henry L.
Ford, Ian
Source
International Journal of Hypertension
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-01-10
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Patients with diabetes mellitus and symptomatic coronary artery disease are also likely to be hypertensive and, overall, are at very high cardiovascular (CV) risk.
This paper reports the findings of a posthoc analysis of the 1113 patients with diabetes mellitus in the ACTION trial: ACTION itself showed that outcomes in patients with stable angina and hypertension were significantly improved when a long-acting calcium channel blocking drug (nifedipine GITS) was added to their treatment regimens.
This further analysis of the ACTION database in those patients with diabetes has identified a number of practical therapeutic issues which are still relevant because of potential outcome benefits, particularly in relation to BP control.
For example, despite background CV treatment and, specifically, despite the widespread use of ACE Inhibitor drugs, the addition of nifedipine GITS was associated with significant benefits: improvement in BP control by an average of 6/3 mmHg and significant improvements in outcome.
In summary, this retrospective analysis has identified that the addition of nifedipine GITS resulted in improved BP control and significant outcome benefits in patients with diabetes who were at high CV risk.
There is evidence to suggest that these findings are of direct relevance to current therapeutic practice.
American Psychological Association (APA)
Elliott, Henry L.& Lloyd, Suzanne M.& Ford, Ian& Meredith, Peter A.. 2011. Improving Blood Pressure Control in Patients with Diabetes Mellitus and High Cardiovascular Risk. International Journal of Hypertension،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-475805
Modern Language Association (MLA)
Elliott, Henry L.…[et al.]. Improving Blood Pressure Control in Patients with Diabetes Mellitus and High Cardiovascular Risk. International Journal of Hypertension No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-475805
American Medical Association (AMA)
Elliott, Henry L.& Lloyd, Suzanne M.& Ford, Ian& Meredith, Peter A.. Improving Blood Pressure Control in Patients with Diabetes Mellitus and High Cardiovascular Risk. International Journal of Hypertension. 2011. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-475805
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475805