MR Imaging Findings in Alcoholic and Nonalcoholic Acute Wernicke’s Encephalopathy : A Review
Joint Authors
De Gennaro, Angela
Cozzolino, Attilio
Serino, Antonietta
Fenza, Giacomo
Manto, Andrea
Manzo, Gaetana
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-24
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Wernicke’s encephalopathy (WE) is a severe neurological syndrome caused by thiamine (vitamin B1) deficiency and clinically characterized by the sudden onset of mental status changes, ocular abnormalities, and ataxia.
Apart from chronic alcoholism, the most common cause of WE, a lot of other conditions causing malnutrition and decreasing thiamine absorption such as gastrointestinal surgical procedures and hyperemesis gravidarum must be considered as predisposing factors.
Due to its low prevalence and clinical heterogeneity, WE is often misdiagnosed, leading to persistent dysfunctions and, in some cases, to death.
Nowadays, MR imaging of the brain, showing T2 and FLAIR hyperintensities in typical (thalami, mammillary bodies, tectal plate, and periaqueductal area) and atypical areas (cerebellum, cranial nerve nuclei, and cerebral cortex), is surely the most important and effective tool in the diagnostic assessment of WE.
The aim of this paper is to propose a state of the art of the role of MR imaging in the early diagnosis of this complex disease.
American Psychological Association (APA)
Manzo, Gaetana& De Gennaro, Angela& Cozzolino, Attilio& Serino, Antonietta& Fenza, Giacomo& Manto, Andrea. 2014. MR Imaging Findings in Alcoholic and Nonalcoholic Acute Wernicke’s Encephalopathy : A Review. BioMed Research International،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-476798
Modern Language Association (MLA)
Manzo, Gaetana…[et al.]. MR Imaging Findings in Alcoholic and Nonalcoholic Acute Wernicke’s Encephalopathy : A Review. BioMed Research International No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-476798
American Medical Association (AMA)
Manzo, Gaetana& De Gennaro, Angela& Cozzolino, Attilio& Serino, Antonietta& Fenza, Giacomo& Manto, Andrea. MR Imaging Findings in Alcoholic and Nonalcoholic Acute Wernicke’s Encephalopathy : A Review. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-476798
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476798