Epigenetics in Critical Illness : A New Frontier
Joint Authors
Graves, Brian T.
Munro, Cindy L.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-09
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Epigenetics is the study of alterations in the function of genes that do not involve changes in the DNA sequence.
Within the critical care literature, it is a relatively new and exciting avenue of research in describing pathology, clinical course, and developing targeted therapies to improve outcomes.
In this paper, we highlight current research relative to critical care that is focused within the major epigenetic mechanisms of DNA methylation, histone modification, microRNA regulation, and composite epigenetic scoring.
Within this emerging body of research it is quite clear that the novel therapies of the future will require clinicians to understand and navigate an even more complex and multivariate relationship between genetic, epigenetic, and biochemical mechanisms in conjunction with clinical presentation and course in order to significantly improve outcomes within the acute and critically ill population.
American Psychological Association (APA)
Graves, Brian T.& Munro, Cindy L.. 2013. Epigenetics in Critical Illness : A New Frontier. Nursing Research and Practice،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-476807
Modern Language Association (MLA)
Graves, Brian T.& Munro, Cindy L.. Epigenetics in Critical Illness : A New Frontier. Nursing Research and Practice No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-476807
American Medical Association (AMA)
Graves, Brian T.& Munro, Cindy L.. Epigenetics in Critical Illness : A New Frontier. Nursing Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-476807
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476807