“Humanized” Stem Cell Culture Techniques : The Animal Serum Controversy
Joint Authors
Gunasingh, Gency Ponrose
Sankaranarayanan, Kavitha
Cherian, K. M.
Tekkatte, Chandana
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-03
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
Cellular therapy is reaching a pinnacle with an understanding of the potential of human mesenchymal stem cells (hMSCs) to regenerate damaged tissue in the body.
The limited numbers of these hMSCs in currently identified sources, like bone marrow, adipose tissue, and so forth, bring forth the need for their in vitro culture/expansion.
However, the extensive usage of supplements containing xenogeneic components in the expansion-media might pose a risk to the post-transplantation safety of patients.
This warrants the necessity to identify and develop chemically defined or “humanized” supplements which would make in vitro cultured/processed cells relatively safer for transplantation in regenerative medicine.
In this paper, we outline the various caveats associated with conventionally used supplements of xenogenic origin and also portray the possible alternatives/additives which could one day herald the dawn of a new era in the translation of in vitro cultured cells to therapeutic interventions.
American Psychological Association (APA)
Tekkatte, Chandana& Gunasingh, Gency Ponrose& Cherian, K. M.& Sankaranarayanan, Kavitha. 2011. “Humanized” Stem Cell Culture Techniques : The Animal Serum Controversy. Stem Cells International،Vol. 2011, no. 2011, pp.1-14.
https://search.emarefa.net/detail/BIM-476903
Modern Language Association (MLA)
Tekkatte, Chandana…[et al.]. “Humanized” Stem Cell Culture Techniques : The Animal Serum Controversy. Stem Cells International No. 2011 (2011), pp.1-14.
https://search.emarefa.net/detail/BIM-476903
American Medical Association (AMA)
Tekkatte, Chandana& Gunasingh, Gency Ponrose& Cherian, K. M.& Sankaranarayanan, Kavitha. “Humanized” Stem Cell Culture Techniques : The Animal Serum Controversy. Stem Cells International. 2011. Vol. 2011, no. 2011, pp.1-14.
https://search.emarefa.net/detail/BIM-476903
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476903