A High Dose Intravenous Immunoglobulin Therapy for Women with Four or More Recurrent Spontaneous Abortions
Joint Authors
Hazama, Ryoichi
Takeda, Masamitsu
Maezawa, Yoko
Yamada, Hideto
Tanimura, Kenji
Shimada, Shigeki
Wakui, Yukio
Ebina, Yasuhiko
Source
ISRN Obstetrics and Gynecology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-11
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Recurrent spontaneous abortion (RSA) may have immunological etiology.
The aim of this study was to assess the efficacy of a high dose intravenous immunoglobulin (HIVIg) therapy, in which 20 g of intact type immunoglobulin was infused daily for 5 days during early gestation, for women who had a history of four or more consecutive spontaneous abortions of unexplained etiology.
A total of 60 pregnant RSA women underwent HIVIg therapy, and the pregnancy outcome was assessed.
The live birth rate was 73.3% (44/60).
Fifteen pregnancies ended in spontaneous abortion, and one ended in intrauterine fetal death.
In 11 of the 15 spontaneous abortions, fetuses had abnormal chromosome karyotype.
When the 11 pregnancies with abnormal chromosome karyotype were excluded, the live birth rate was as high as 89.8% (44/49).
The HIVIg therapy may be effective for severe cases of unexplained RSA.
American Psychological Association (APA)
Yamada, Hideto& Takeda, Masamitsu& Maezawa, Yoko& Ebina, Yasuhiko& Hazama, Ryoichi& Tanimura, Kenji…[et al.]. 2012. A High Dose Intravenous Immunoglobulin Therapy for Women with Four or More Recurrent Spontaneous Abortions. ISRN Obstetrics and Gynecology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-477532
Modern Language Association (MLA)
Yamada, Hideto…[et al.]. A High Dose Intravenous Immunoglobulin Therapy for Women with Four or More Recurrent Spontaneous Abortions. ISRN Obstetrics and Gynecology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-477532
American Medical Association (AMA)
Yamada, Hideto& Takeda, Masamitsu& Maezawa, Yoko& Ebina, Yasuhiko& Hazama, Ryoichi& Tanimura, Kenji…[et al.]. A High Dose Intravenous Immunoglobulin Therapy for Women with Four or More Recurrent Spontaneous Abortions. ISRN Obstetrics and Gynecology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-477532
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477532