BAG3 and HIF-1α Coexpression Detected by Immunohistochemistry Correlated with Prognosis in Hepatocellular Carcinoma after Liver Transplantation
Joint Authors
Zhou, Lin
Lv, Zhen
Tong, Rongliang
Wu, Jian
Xiao, Heng
Zheng, Shusen
Cheng, Shaobing
Du, Chengli
Ding, Chaofeng
Xie, Haiyang
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
The objective is to determine the effects of BAG3 and HIF-1α expression on the prognosis of HCC patients after liver transplantation.
Methods.
Samples from 31 patients with HCC receiving liver transplantation were collected for this study.
The immunohistochemistry was used to detect the expression of BAG3 and HIF-1α of HCC samples.
Results.
According to the immunohistochemistry results, BAG3 and HIF-1α staining were significantly associated with tumor TNM stage (P=0.004, P=0.012).
A significant association between high BAG3/HIF-1α levels and a shorter overall survival was detected, so as the combined BAG3 and HIF-1α analysis.
Conclusion.
The results suggested that the expression level of BAG3 and HIF-1α is efficient prognostic parameters in patients with HCC after liver transplantation.
American Psychological Association (APA)
Xiao, Heng& Tong, Rongliang& Cheng, Shaobing& Lv, Zhen& Ding, Chaofeng& Du, Chengli…[et al.]. 2014. BAG3 and HIF-1α Coexpression Detected by Immunohistochemistry Correlated with Prognosis in Hepatocellular Carcinoma after Liver Transplantation. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-477898
Modern Language Association (MLA)
Xiao, Heng…[et al.]. BAG3 and HIF-1α Coexpression Detected by Immunohistochemistry Correlated with Prognosis in Hepatocellular Carcinoma after Liver Transplantation. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-477898
American Medical Association (AMA)
Xiao, Heng& Tong, Rongliang& Cheng, Shaobing& Lv, Zhen& Ding, Chaofeng& Du, Chengli…[et al.]. BAG3 and HIF-1α Coexpression Detected by Immunohistochemistry Correlated with Prognosis in Hepatocellular Carcinoma after Liver Transplantation. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-477898
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477898
