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Serum Anti-Müllerian Hormone Levels in Patients with Epithelial Ovarian Cancer
Joint Authors
Walentowicz, Pawel
Mankowska-Cyl, Aneta
Sypniewska, Grazyna
Walentowicz-Sadlecka, Małgorzata
Grabiec, Marek
Sadlecki, Pawel
Krintus, Magdalena
Source
International Journal of Endocrinology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-28
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objectives.
The aim of our study was to examine serum anti-Müllerian hormone (AMH) concentration in ovarian cancer patients in relation to clinicopathological features, such as a pathological subtype of the tumor, (FIGO) stage, grading, and overall 5-year survival.
Material and Methods.
We enrolled 72 epithelial ovarian cancer patients in our study, aged 45–79 years, who underwent optimal cytoreductive surgery.
In all patients, serum AMH concentration was measured using a two-step sandwich type enzyme immunoassay before surgery.
As a reference value for women over 45 years we accepted anti-Müllerian hormone concentration below 1 ng/mL.
Results.
In the whole group of patients with ovarian cancer, median serum concentration of AMH was 0.07 (0.0–0.37) ng/mL, whereas in the group of those with positive AMH values (≥0.14 ng/mL) it was 0.31 (0.15–0.73) ng/mL.
No significant correlation was found between serum AMH levels and FIGO stage, histological subtype, or grading (P>0.05).
The analysis of five-year survival rate related to AMH levels showed no statistically significant differences.
There were no differences in survival rates between patients with positive or negative serum AMH levels.
Conclusion.
Measurement of serum anti-Müllerian hormone levels was not useful in predicting clinicopathological features and survival in patients with ovarian cancer.
American Psychological Association (APA)
Walentowicz, Pawel& Sadlecki, Pawel& Krintus, Magdalena& Sypniewska, Grazyna& Mankowska-Cyl, Aneta& Grabiec, Marek…[et al.]. 2013. Serum Anti-Müllerian Hormone Levels in Patients with Epithelial Ovarian Cancer. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-477962
Modern Language Association (MLA)
Walentowicz, Pawel…[et al.]. Serum Anti-Müllerian Hormone Levels in Patients with Epithelial Ovarian Cancer. International Journal of Endocrinology No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-477962
American Medical Association (AMA)
Walentowicz, Pawel& Sadlecki, Pawel& Krintus, Magdalena& Sypniewska, Grazyna& Mankowska-Cyl, Aneta& Grabiec, Marek…[et al.]. Serum Anti-Müllerian Hormone Levels in Patients with Epithelial Ovarian Cancer. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-477962
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477962