Update on the Diagnosis and Management of Refractory Coeliac Disease
Joint Authors
van Wanrooij, Roy L. J.
Bouma, Gerd
Mulder, Chris J. J.
Nijeboer, Petula
Tack, Greetje J.
Source
Gastroenterology Research and Practice
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-09
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
A small subset of coeliac disease (CD) patients experiences persisting or recurring symptoms despite strict adherence to a gluten-free diet (GFD).
When other causes of villous atrophy have been excluded, these patients are referred to as refractory celiac disease (RCD) patients.
RCD can be divided in two types based on the absence (type I) or presence (type II) of an, usually clonal, intraepithelial lymphocyte population with aberrant phenotype.
RCDI usually runs a benign course and may be difficult to be differentiated from uncomplicated, slow responding CD.
In contrast, RCDII can be defined as low-grade intraepithelial lymphoma and frequently transforms into an aggressive enteropathy associated T-cell lymphoma with dismal prognosis.
This paper describes the clinical characteristics of RCDI and RCDII, diagnostic approach, and the latest insights in treatment options.
American Psychological Association (APA)
Nijeboer, Petula& van Wanrooij, Roy L. J.& Tack, Greetje J.& Mulder, Chris J. J.& Bouma, Gerd. 2013. Update on the Diagnosis and Management of Refractory Coeliac Disease. Gastroenterology Research and Practice،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-478087
Modern Language Association (MLA)
Nijeboer, Petula…[et al.]. Update on the Diagnosis and Management of Refractory Coeliac Disease. Gastroenterology Research and Practice No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-478087
American Medical Association (AMA)
Nijeboer, Petula& van Wanrooij, Roy L. J.& Tack, Greetje J.& Mulder, Chris J. J.& Bouma, Gerd. Update on the Diagnosis and Management of Refractory Coeliac Disease. Gastroenterology Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-478087
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-478087