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New Insights into the p38γ and p38δ MAPK Pathways
Joint Authors
Source
Journal of Signal Transduction
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The mammalian p38 mitogen-activated protein kinases (MAPKs) family is composed of four members (p38α, p38β, p38γ, and p38δ), which are very similar in amino acid sequence but differ in their expression patterns.
This suggests that they may have specific functions in different organs.
In the last years most of the effort has been centred on the study of the function of the p38α isoform, which is widely referred to as p38 in the literature.
However, the role that other p38 isoforms play in cellular functions and their implication in some of the pathological conditions have not been precisely defined so far.
In this paper we highlight recent advances made in defining the functions of the two less studied alternative p38MAPKs, p38γ and p38δ.
We describe that these p38MAPKs show similarities to the classical p38α isoform, although they may play central and distinct role in certain physiological and pathological processes.
American Psychological Association (APA)
Risco, Ana& Cuenda, Ana. 2011. New Insights into the p38γ and p38δ MAPK Pathways. Journal of Signal Transduction،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-478248
Modern Language Association (MLA)
Risco, Ana& Cuenda, Ana. New Insights into the p38γ and p38δ MAPK Pathways. Journal of Signal Transduction No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-478248
American Medical Association (AMA)
Risco, Ana& Cuenda, Ana. New Insights into the p38γ and p38δ MAPK Pathways. Journal of Signal Transduction. 2011. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-478248
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-478248