Cytokines and Chemokines as Regulators of Skeletal Muscle Inflammation : Presenting the Case of Duchenne Muscular Dystrophy

Joint Authors

De Paepe, Boel
De Bleecker, Jan L.

Source

Mediators of Inflammation

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-11-05

Country of Publication

Egypt

No. of Pages

10

Main Subjects

Diseases

Abstract EN

Duchenne muscular dystrophy is a severe inherited muscle disease that affects 1 in 3500 boys worldwide.

Infiltration of skeletal muscle by inflammatory cells is an important facet of disease pathophysiology and is strongly associated with disease severity in the individual patient.

In the chronic inflammation that characterizes Duchenne muscle, cytokines and chemokines are considered essential activators and recruiters of inflammatory cells.

In addition, they provide potential beneficiary effects on muscle fiber damage control and tissue regeneration.

In this review, current knowledge of cytokine and chemokine expression in Duchenne muscular dystrophy and its relevant animal disease models is listed, and implications for future therapeutic avenues are discussed.

American Psychological Association (APA)

De Paepe, Boel& De Bleecker, Jan L.. 2013. Cytokines and Chemokines as Regulators of Skeletal Muscle Inflammation : Presenting the Case of Duchenne Muscular Dystrophy. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-479885

Modern Language Association (MLA)

De Paepe, Boel& De Bleecker, Jan L.. Cytokines and Chemokines as Regulators of Skeletal Muscle Inflammation : Presenting the Case of Duchenne Muscular Dystrophy. Mediators of Inflammation No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-479885

American Medical Association (AMA)

De Paepe, Boel& De Bleecker, Jan L.. Cytokines and Chemokines as Regulators of Skeletal Muscle Inflammation : Presenting the Case of Duchenne Muscular Dystrophy. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-479885

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-479885