SPECT Imaging Agents for Detecting Cerebral β-Amyloid Plaques
Joint Authors
Source
International Journal of Molecular Imaging
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-13
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The development of radiotracers for use in vivo to image β-amyloid (Aβ) plaques in cases of Alzheimer's disease (AD) is an important, active area of research.
The presence of Aβ aggregates in the brain is generally accepted as a hallmark of AD.
Since the only definitive diagnosis of AD is by postmortem staining of affected brain tissue, the development of techniques which enable one to image Aβ plaques in vivo has been strongly desired.
Furthermore, the quantitative evaluation of Aβ plaques in the brain could facilitate evaluation of the efficacy of antiamyloid therapies currently under development.
This paper reviews the current situation in the development of agents for SPECT-based imaging of Aβ plaques in Alzheimer's brains.
American Psychological Association (APA)
Ono, Masahiro& Saji, Hideo. 2011. SPECT Imaging Agents for Detecting Cerebral β-Amyloid Plaques. International Journal of Molecular Imaging،Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-480196
Modern Language Association (MLA)
Ono, Masahiro& Saji, Hideo. SPECT Imaging Agents for Detecting Cerebral β-Amyloid Plaques. International Journal of Molecular Imaging No. 2011 (2011), pp.1-12.
https://search.emarefa.net/detail/BIM-480196
American Medical Association (AMA)
Ono, Masahiro& Saji, Hideo. SPECT Imaging Agents for Detecting Cerebral β-Amyloid Plaques. International Journal of Molecular Imaging. 2011. Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-480196
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-480196