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New Formulations of Local Anaesthetics—Part I
Author
Source
Anesthesiology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-05
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Part 1 comments on the types of local anaesthetics (LAs); it provides a better understanding of the mechanisms of action of LAs, and their pharmacokinetics and toxicity.
It reviews the newer LAs such as levobupivacaine, ropivacaine, and articaine, and examines the newer structurally different LAs.
The addition of adjuvants such as adrenaline, bicarbonate, clonidine, and corticosteroids is explored.
Comment is made on the delivery of topical LAs via bioadhesive plasters and gels and controlled-release local anaesthetic matrices.
Encapulation matrices such as liposomes, microemulsions, microspheres and nanospheres, hydrogels and liquid polymers are discussed as well.
New innovations pertaining to LA formulations have indeed led to prolonged action and to novel delivery approaches.
American Psychological Association (APA)
Shipton, Edward A.. 2011. New Formulations of Local Anaesthetics—Part I. Anesthesiology Research and Practice،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-480376
Modern Language Association (MLA)
Shipton, Edward A.. New Formulations of Local Anaesthetics—Part I. Anesthesiology Research and Practice No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-480376
American Medical Association (AMA)
Shipton, Edward A.. New Formulations of Local Anaesthetics—Part I. Anesthesiology Research and Practice. 2011. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-480376
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-480376